The antimicrobial activity of luteolin against four bacteria in vitro
10.16303/j.cnki.1005-4545.2017.08.23
- VernacularTitle:木犀草素对4种细菌体外抗菌活性研究
- Author:
Chengcheng HUANG
;
Xiang GAO
;
Tingting SUN
;
Lihui YU
;
Yang GUO
;
Wei HONG
;
Dexian ZHANG
;
Mingchun LIU
- Keywords:
luteolin;
antimicrobial activity;
growth curve of bacteria
- From:
Chinese Journal of Veterinary Science
2017;37(8):1558-1561
- CountryChina
- Language:Chinese
-
Abstract:
Broth microdilution method was hired to measure the minimum inhibitory concentrations (MICs) of luteolin against Trueperella pyogenes,Escherichia coli,Salmonella and Streptococcus in order to evaluate the antimicrobial activity of luteolin in vitro.Meanwhile,the bacteria growth curves in medium containing sub-inhibitory concentration of luteolin were measured in this test.The results indicated that Tureperella pyogenes was the most sensitive to luteolin with a MIC of 0.078 g/L than that of these strains;and Salmonella was also sensitive to luteolin (MIC:1.25 g/L).However,The inhibitory effect of luteolin on Escherichia coli and Streptococcus is relatively weak,and shared the same MIC with 2.5 g/L.Luteolin showed inhibitory effects on the growth curves of all the strains in this test at sub-inhibitory concentration,and the inhibitory effects on the growth curves increased with the concentration of luteolin(P＜0.05).
