Effect of Laparoscopic Minimally Invasive on Anorectal Dynamics and Serum CEA and CA724 in Patients with Rectal Cancer
10.13241/j.cnki.pmb.2017.22.019
- VernacularTitle:腹腔镜微创对直肠癌患者肛肠动力学及血清CEA,CA724水平的影响
- Author:
Yinshengboer BAO
;
Yongjing TIAN
;
Tengqi WANG
;
Haibin SUN
;
Haiping FENG
;
Riletu EN
;
Jian PANG
;
Hongliang JIANG
;
Yaodong JIA
- Keywords:
Rectal cancer;
Laparoscopic minimally invasive;
Anorectal dynamics;
CEA;
CA724
- From:
Progress in Modern Biomedicine
2017;17(22):4285-4288
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effect of laparoscopic minimally invasive on anorectal dynamics and serum carcino-embryonic antigen (CEA) and carbohydrate antigen 724 (CA724) in patients with rectal cancer.Methods:38 cases of rectal cancer patients were selected as the research group from March 2014 to March 2016 and 40 cases of non neoplastic intestinal polyps as control group,Preoperative anorectal dynamics index (anal resting pressure (ARP),rectal resting pressure (RRP)and anal maximal contraction pressure (MSP),rectal maximum tolerated volume (MTV) of two groups were compared,Preoperative and 3 d,1,2 weeks after operation of serum CEA and CA724 levels were detected in the research group and the clinical curative effect was observed.Results:There was no significant difference of ARP,RRP,MSP,MTV before operation in research group compared with the control group(P＞0.05),and was significantly reduced 2,4 weeks after operation(P＜0.05),then gradually restored,and basically recovered to the preoperative level 12 weeks after operation.There was no significant difference of serum CEA and CA724 levels 3 d after operation compared with preoperative in research group (P＞0.05),and were significantly lower 1,2 weeks after operation compared with preoperative (P＜0.05).The clinical effective rate was 65.8％.Conclusion:Efficacy of laparoscopic minimally invasive in treatment of rectal cancer is effective,can effectively reduce the levels of tumor markers,although there are some influence on anorectal dynamics,but it can be returned to normal in the short term.
