Research and application of colistin in animals
10.16303/j.cnki.1005-4545.2017.08.34
- VernacularTitle:黏杆菌素在动物中的研究与应用
- Author:
Guyue CHENG
;
Jun LI
;
Haihong HAO
;
Xu WANG
;
Zhenli LIU
;
Zonghui YUAN
- Keywords:
colistin;
antibacterial action;
pharmacokinetics;
application;
drug resistance
- From:
Chinese Journal of Veterinary Science
2017;37(8):1617-1626
- CountryChina
- Language:Chinese
-
Abstract:
Colistin is a kind of old cationic drug,which can interfere bacterial cell membrane,thus to cause bacterial death.It is mainly used for the treatment of infections caused by Gram-negative bacteria,and its antimicrobial activity against multidrug-resistant Gram-negative bacteria is also very significant.At present,colistin is widely used in veterinary medicine.This article aims to review colistin in chemical,pharmacological,and pharmacokinetic studies,and also summarizes the application and resistance of this drug,which will provide reference for the reasonable selection and use of this drug in animals.
