Transcatheter hepatic arterial chemoembolization combined with CT-guided thermal ablation for the treatment of intrahepatic cholangiocarcinoma
10.3969/j.issn.1008-794X.2017.07.010
- VernacularTitle:肝动脉化疗栓塞联合CT引导热消融治疗肝内胆管癌
- Author:
Shoupeng SHENG
;
Jiasheng ZHENG
;
Shichang CUI
;
Xiongwei CUI
;
Zhiling QIAN
;
Jianjun LI
;
Honghai ZHANG
;
Xiaozhen YANG
;
Liang MA
- Keywords:
intrahepatic cholangiocarcinoma;
hepatic arterial chemoembolization;
radiofrequency ablation;
microwave ablation
- From:
Journal of Interventional Radiology
2017;26(7):618-621
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy and safety of transcatheter arterial chemoembolization (TACE) combined with CT-guided thermal ablation (radiofrequency ablation or microwave ablation) in treating intrahepatic cholangiocarcinoma.Methods The clinical data of 14 patients with pathologicallyproved intrahepatic cholangiocarcinoma,who were admitted to authors' hospital during the period from September 2009 to July 2013 to receive TACE with subsequent radiofrequency ablation (RFA) or microwave ablation (MWA),were retrospectively analyzed.A total of 18 lesions were detected in the 14 patients.The maximal diameter of the lesion (or the sum of maximal diameters if there were multiple lesions) ranged from 2.2 cm to 7.2 cm (mean 4.2±1.4 cm).After TACE,the lesion's complete ablation rate,surgical complications,tumor-free survival time and overall survival time were evaluated.Results Complete ablation was obtained in 15 lesions (83.3％,15/18).The incidence of moderate complications was 6.2％,and no severe complications or death occurred.After the treatment,the patients were followed up for 6-14 months,with a mean of (16.0±10.3) months.At the end of follow-up,6 patients (42.9％,6/14) died.The median tumor-free survival time in patients whose lesions obtained complete ablation was 17 months.The median survival time of all patients was 20 months.The 1-,2-and 3-year overall survival rates were 82.5％,41.3％ and 20.6％ respectively.Conclusion TACE combined with thermal ablation can be regarded as one of the treatment options for intrahepatic cholangiocarcinoma.
