A Study on the Perioperative Clinical Efficacy of Restrictive Blood Transfusion Combined with Hyperbaric Oxygen Preconditioning on the THA and TKA
10.13241/j.cnki.pmb.2017.26.026
- VernacularTitle:限制性输血联合高压氧预处理对THA、TKA围术期临床疗效的研究
- Author:
Jing LIANG
;
Ling QI
;
Na FAN
;
Xiaofei GUO
;
Xia GUI
- Keywords:
Restrictive blood transfusion;
Hyperbaric oxygen;
Preconditioning;
Total hip/kneeathroplasty;
THA/TKA
- From:
Progress in Modern Biomedicine
2017;17(26):5120-5123
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the clinical effects of restrictive blood transfusion combined with hyperbaric oxygen preconditioning (HBOPC) and restrictive blood transfusion in the treatment of hip,knee arthroplasty (THA,THA).Methods:40 patients in the period of epidural anesthesia,femoral nerve hysteresis hip and knee arthroplasty were selected and randomly divided into two groups:restrictive transfusion group (maintain 80 g/L≤ Hb <100 g/L,n=20) and restrictive blood transfusion combined with HBOPC (HBOPC+maintain 80 g/L =Hb <100 g/L,n=20).The red blood cell transfusion,red blood cell transfusion rate,perioperative Hb,blood oxygen saturation (SO2),the incidence of hypotension during operation,hospitalization time and postoperative cerebral infarction,acute pulmonary embolism,pneumonia,myocardial infarction,wound infection rate and 90 days mortality rate were compared between two groups.Results:Compared with the restrictive transfusion group,the postoperative Hb,blood oxygen saturation (SO2) of restrictive blood transfusion combined with HBOPC group were significantly increased(P < 0.05);the red blood cell transfusion,red blood cell transfusion rate,incidence of pneumonia,wound infection rate were significantly decreased (P<0.05).Conclusion:Restrictive blood transfusion combined with hyperbaric oxygen preconditioning could improve the anoxic state of the hip,knee arthroplasty patients,which could effectively reduce red blood cell transfusion,reduce postoperative complications,has good clinical curative effect.