The Research Progress of Essential Hypertension Related Gene DNA Methylation
10.13241/j.cnki.pmb.2017.26.046
- VernacularTitle:原发性高血压相关基因DNA甲基化的研究进展
- Author:
Li LI
;
Zhaoqing YANG
- Keywords:
Hypertension;
Candidate gene;
DNA methylation
- From:
Progress in Modern Biomedicine
2017;17(26):5197-5200
- CountryChina
- Language:Chinese
-
Abstract:
Hypertension is a common and chronic disease,and is also the mainly risk factor of cardio-cerebrovascular disease.Essential hypertension is a complex disease caused by the common function of multiple genes and environmental factors,but the exact pathogenesis is still unclear.With the study continues,the role of DNA methylation and other epigenetic factors in pathological process with essential hypertension (EH) gradually be taken seriously.This review summarizes the research progress of some essential hypertension related methylation genes' function in the course of hypertension,to explain the relationship between DNA methylation markers which can be influenced by environment factor and essential hypertension and help us have a further understanding about the hypertension pathogenesis.
