Diagnosis of Dynamic Contrast-enhanced Magnetic Resonance Imaging and Diffusion Tensor Imaging in Benign and Malignant Nodules of Central Prostate Gland
10.3969/j.issn.1005-5185.2017.07.020
- VernacularTitle:动态增强磁共振与扩散张量成像对前列腺中央区良恶性结节的诊断价值
- Author:
Huizhen SONG
;
Lin ZHANG
- Keywords:
Prostatic neoplasms;
Magnetic resonance imaging;
Diffusion tensor imaging;
Image enhancement;
Pathology,surgical;
Diagnosis,differential
- From:
Chinese Journal of Medical Imaging
2017;25(7):550-554
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To study the diagnostic value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI),diffusion tensor imaging (DTI) and the combination of these two techniques in benign and malignant nodules of central prostate gland.Materials and Methods Forty-nine patients with nodular abnormal signal in central prostate gland who had accepted prostate MRI scan in Shihezi University Medical College First Affiliated Hospital from September 2015 to December 2016 were retrospectively analyzed,and all the subjects had accepted MRI T2WI,DTI and DCE scan.The pathological results confirmed that there were 21 prostate cancer (PCa) and 36 benign prostatic hyperplasia (BPH) among 57 central gland nodule samples.The fractional anisotropy value,apparent diffusion coefficient value,time to peak,SImax,the curve slope and timesignal intensity curve of nodules were respectively detected,the differences of the parameters between PCa group and BPH group were compared,and receiver operating characteristic (ROC) curve analysis was carried out.Results The difference of fractional anisotropy value,apparent diffusion coefficient value,time to peak and R between PCa group and BPH group was statistically significant (P＜0.05),and there was no significant difference in SImax (P＞0.05);the time-signal intensity curve type of PCa group was mainly in the form of fast-increasing and then decreasing,while the curve type of BPH group was mainly in the form of platform.The area under the ROC curve of DCE,DTI and the combination of DEC and DTI were 0.87 (95％ CI:0.751-0.942),0.85 (95％ CI:0.734-0.933) and 0.94 (95％ CI:0.837-0.983),respectively.Conclusion In the cases of diagnosing benign and malignant nodules of central prostate gland,the accuracy of DTI and DCE was lower than that of the combination of these two techniques,and the diagnostic effect of DTI combined with DCE was better.
