Aterial Spin Labeling Evaluation of Residual Renal Function After Partial Nephrectomy on Renal Cell Carcinoma
10.3969/j.issn.1005-5185.2017.07.021
- VernacularTitle:动脉自旋标记MRI评价肾癌部分切除术后残余肾功能的价值
- Author:
Chenglong WEN
;
Tao REN
;
Lihua CHEN
;
Lixiang HUANG
;
Shuangshuang XIE
;
Chao CHAI
;
Qian LIU
;
Wen SHEN
- Keywords:
Carcinoma,renal cell;
Nephrectomy;
Laparoscopy;
Magnetic resonance imaging;
Renal blood flow
- From:
Chinese Journal of Medical Imaging
2017;25(7):555-558
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To investigate the value of arterial spin labeling (ASL) in evaluating renal function in patients with renal cell carcinoma (RCC) after laparoscopic partial nephrectomy.Materials and Methods Fifteen patients with RCC undergoing laparoscopic partial nephrectomy were studied prospectively.The patients were performed ASL scan one week before and three months after operation.The correlation between renal blood flow (RBF) value measured by ASL and the glomerular filtration rate (GFR) measured by radionuclide method in the renal cortex of healthy side was analyzed.The RBF values in the kidney of affected side or healthy side were measured,the difference of which between before operation and three months after operation was compared.Results The RBF value and GFR data in the renal cortex of healthy side had positive correlation (r=0.638,P<0.05).In the affected side of kidney,the RBF value of remaining renal tissue [(291.5 ± 37.3) ml/(100g·min)] compared with that of preoperative renal tissue [(237.8 ± 46.2) ml/(100g·min)]increased about 53.7 ml/(100g · min) (P<0.05).In the healthy side of kidney,the RBF value of renal tissue [(241.1 ± 50.3) ml/(100 g · min)] compared with that of preoperative renal tissue [(290.4 ± 51.8) ml/(100 g·min)] decreased about 49.3 ml/(100 g·min) (P<0.05).Conclusion ASL can be used to evaluate renal function,and it is valuable to evaluate renal perfusion function after laparoscopic partial nephrectomy of RCC.