Relationship Between Maximum Standardized Uptake Value of 18F-FDG PET/CT and Clinical Features of Tongue Squamous Cell Carcinoma
10.3969/j.issn.1005-5185.2017.07.001
- VernacularTitle:18F-FDG PET/CT最大标准化摄取值与舌鳞状细胞癌临床特征的关系
- Author:
Dong ZHENG
;
Lixuan NIU
;
Jiahe TIAN
;
Ke LI
;
Junhua LIU
;
Jun FEI
- Keywords:
Tongue neoplasms;
Neoplasms,squamous cell;
Positron-emission tomography;
Tomography,X-ray computed;
Fluorodeoxyglucose F18;
Pathology,surgical
- From:
Chinese Journal of Medical Imaging
2017;25(7):481-486
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To investigate the relationship between maximum standardized uptake value (SUVmax) of 18F-FDG PET/CT and clinical features of tongue squamous cell carcinoma (TSCC),in order to provide better PET/CT results for clinical guide.Materials and Methods Fifty-two patients with pathologically confirmed TSCC who accepting PET/CT examination before surgery were retrospectively analyzed.Single-factor analysis and multiple regression analysis were conducted on possible factors influencing primary tumor SUVmax,including gender,age,smoking history,tumor location,tumor size,TNM stage,T stage and N stage.Results Single-analysis showed that SUVmax was correlated with gender,tumor location,tumor size,TNM stage,T stage and N stage (P＜0.05),and was not correlated with tumor differentiation,smoking history and age (P＞0.05).Multivariate linear regression analysis showed that gender,tumor location,tumor size,T stage and N stage were independent influencing factors of primary tumor SUVmax (P＜0.05).Primary tumor SUVmax had predictive value for lymph node metastasis.When the cutoff value was 6.57,the diagnostic efficiency was the highest,the sensitivity was 79.2％ and the specificity was 85.7％.Conclusion TSCC 18F-FDG PET/CT SUVmax is higher among male patients with tongue base tumor location,larger tumor size and lymph node metastasis.Primary tumor SUVmax is of important significance in predicting lymph node metastasis.
