Clinical Effect of Modified Simiao San Compared and Colchicine in the Treatment of Damp Heat Gout
10.13241/j.cnki.pmb.2017.25.027
- VernacularTitle:四妙散加味和秋水仙碱治疗湿热蕴结型痛风的疗效观察
- Author:
Lei FENG
;
Ruixia PEI
;
Xingbo LI
;
Xiaoli LI
;
Yanfang WANG
- Keywords:
Damp Heat Gout;
Modified Simiao San;
Colchicine;
Life quality
- From:
Progress in Modern Biomedicine
2017;17(25):4912-4915
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the clinical effect and safety of modified Simiao San and colchicines on the damp heat gout.Methods:120 patients with damp heat gout admitted in our hospital in 2015 were selected and randomly divided into group A,group B and group C with 40 cases in each group.Patients in group A were given modified Simiao San,patients in group B were given colchicine,patients in group C were given modified Simiao San combined with colchicine.Then the clinical effect,scores of symptoms,expression levels of inflammatory factors and other biochemical indexes,adverse reactions and recurrence rate of 3 groups were compared berween three groups.Results:The total effective rate and effectually effective rate of group A were 92.5％ and 57.5％ respectively,which were 95.0％ and 65.0％ in group C was,obviously higher than 77.5％ and 35.0％ of group B (P＜0.05).The symptom scores of 3 groups after treatment were all lower than those before treatment (P＜0.05).The variety of ESR and UA of group C were greater than other groups (P＜0.05).The incidence rate of adverse reaction in group A and group C were 5.0％ and 7.5％ respectively,obviously lower than 22.5 of group B with statistically signficance (P＜0.05).The SF-36 score of group C was obviously lower than those of group A and group B with statistically significance (P＜0.05).Conclusion:Modified Simiao San combined with colchicine had better effect and safety compared to single medicine,which could greatly improve the quality of life.
