Quantitative features and diagnostic value of 3-dimensional shear wave elastography in breast lesions
10.3760/cma.j.issn.1004-4477.2017.07.013
- VernacularTitle:乳腺病灶三维实时剪切波弹性成像定量特征及其诊断价值
- Author:
Yaling CHEN
;
Yi GAO
;
Fen WANG
;
Na LI
;
Aiyu MIAO
;
Wenxiang ZHI
;
Cai CHANG
- Keywords:
Ultrasonography,three-dimensional;
Breast diseases;
Shear wave elastography
- From:
Chinese Journal of Ultrasonography
2017;26(7):613-617
- CountryChina
- Language:Chinese
-
Abstract:
Objective To retrospectively study the quantitative features and diagnostic value of 3-dimensional shear wave elastography (3D-SWE) in breast lesions.Methods A total of 198 consecutive women with 198 breast lesions (125 malignant,73 benign) were included,who underwent conventional ultrasound (US) and 3D-SWE before surgical excision.Quantitative parameters of transverse planes,sagittal planes and coronal planes were calculated,including maximum elasticity (Emax-w),mean elasticity (Emean-w),standard deviation (Esd) of the whole lesion and ratio between the stiffest elasticity (Emean-s)in the lesion and the fatty tissue (Eratio).Area under ROC curve(AUC) for combination of quantitative parameters and US were calculated.Results The AUC,sensitivity and specificity for US were 0.919,88.0% and 78.1 %,respectively.In the total 198 lesions,Emax-w,Emean-w,Esd,Eratio and Emean s were significantly lower in coronal planes than those in transverse and sagittal planes (all P <0.001).AUC for combination of each quantitative parameter and US were significantly higher than those of US (all P <0.05),except Emean-w of transverse plane,while there was no significant difference among the three orthogonal plane (P>0.05).Sensitivity significantly increased by combining US with Emean-s,Eratio (transverse,sagittal and coronal planes),Emean-w (coronal and sagittal planes) or Esd (coronal and transverse planes) (all P<0.05).Combination of US and Emean w of coronal plane yielded significantly higher sensitivity than those of transverse and sagittal planes.Conclusions Combination of quantitative features of 3D-SWE and US can significantly increase diagnostic accuracy and sensitivity in breast lesions.Emean-w of coronal plane yields the highest sensitivity.