Clincal Value of Ultrasound-guided Transvaginal Radiofrequency Ablation for the Treatment of Symptomatic Uterine Fibroid
10.13241/j.cnki.pmb.2017.23.015
- VernacularTitle:超声引导经阴道射频消融治疗症状性子宫肌瘤的临床价值
- Author:
Liwei ZHANG
;
Xiaoqiu DONG
;
Yunfeng QI
;
Dejiao KONG
;
Yawen CAI
;
Qian LV
;
Jingyu DUAN
- Keywords:
Radiofrequency ablation;
Uterine fibroid;
Ultrasound-guided;
Symptomatic uterine fibroid
- From:
Progress in Modern Biomedicine
2017;17(23):4471-4474
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the safety and efficacy of ultrasound-guided transvaginal radiofrequency ablation in the treat ment of symptomatic uterine fibroid.Methods:39 patients with symptomatic uterine fibroid underwent transvaginal radiofrequency ablation therapy were selected Before treatment,the fibroid size and volume were measured using ultrasound.The fibroid-related symptom severity and quality of life were scored using uterine fibroid symptom and quality of life survey.The fibroid volume reduction rate,improvement in clinical symptom and quality of life,and ovarian function of patients were observed before treatment and at three,six,nine and 12 months after treatment.Results:The average operation time of radiofrequency ablation was 25 minutes.There was no clear intraand postoperative complication.Preoperative fibroid volume was 65.2± 49.3cm3,which was reduced to 32.2± 27.6 cm3,21.2± 18.2 cm3,15.3± 12.1 cm3 and 10.3± 9.8 cm3 at 3,6,9 and 12 months after treatment,respectively(P<0.05).The symptom severity score (SSS) was 60.23± 13.2 before treatment,and gradually decreased to 42.2± 11.4,21.1± 10.2,15.4± 10.3 and 12.2± 9.7 at 3,6,9 and 12 months after treatment(P<0.05).The quality of life (QOL) score gradually increased from 58.24± 16.24 before treatment to 70.3± 20.3,81.4± 8.6,86.3± 7.6 and 88.2± 9.1 at 3,6,9 and 12 months after treatment (P<0.05).The levels of follicle stimulating hormone,luteinizing hormone and estradiol at 3,6,9 and 12 months after treatment showed no difference compared with these before treatment (P>0.05).Conclusions:Ultrasound-guided transvaginal radiofrequency therapy was a minimally invasive,safe,and effective therapy for symptomatic uterine fibroid.