Advances of microRNA activity in innate immunity
10.11665/j.issn.1000-5048.20170403
- VernacularTitle:microRNA在固有免疫中的作用研究进展
- Author:
Ruocong YANG
;
Feipeng DUAN
;
Jiahong CHAO
;
Pengpeng TIAN
;
Zhiyong YAN
;
Shaojing LI
- Keywords:
microRNA;
innate immune;
inflammation;
advances
- From:
Journal of China Pharmaceutical University
2017;48(4):396-406
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA (miRNA),sharing the character of regulating the transcriptional level and expression level of mRNAs,is one kind of small non-coded RNAs.At present,innate immune has become one of the hot topics for researchers,and miRNAs as a sort of bioactive substance greatly take part in the whole regulation progress.In detailed,miRNAs can influence the immune state of immune cells during innate immune period and further regulate inflammatory conditions in whole body.By systematically summarizing miRNA function during innate immunity,this present review may provide a reference for peer researchers.
