Osteoporosis Prevalence of Radius and Tibia and Related Factors Using Multiple Bone Sites Quantitative Ultrasound Measurement of the Korean Health and Genome Study Cohort Women.
- Author:
Seon Joo PARK
1
;
Younjhin AHN
;
Hae Sook MIN
;
Kyoung Soo OH
;
Chan PARK
;
Nam Han CHO
;
Kuchan KIMM
Author Information
1. National Genome Research Institute, National Institute of Health, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
osteoporosis prevalence;
QUS (Quantitative Ultrasound);
BMI;
Ca and Ca/P intake
- MeSH:
Aging;
Bone Density;
Bone Diseases, Metabolic;
Cohort Studies*;
Education;
Female;
Genome*;
Gyeonggi-do;
Humans;
Logistic Models;
Metabolism;
Odds Ratio;
Osteoporosis*;
Prevalence*;
Radius*;
Riboflavin;
Tibia*;
Ultrasonography*;
Vitamin B 6;
Vitamin E;
Vitamins
- From:Korean Journal of Community Nutrition
2005;10(4):536-545
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This study was conducted to investigate osteopenia and osteoporosis prevalence of radius and tibia using Quantitative Ultrasound (QUS) and to identify affecting factors of osteoporosis. A total of 4,340 women aged 40 - 69 years, living in Ansung (rural) and Ansan (mid-sized) area, and free of illnesses affecting bone metabolism participated in the community-based cohort study. Among them 4,059 subjects measured radius bone density and 4,089 measured tibia. The T-score threshold, defined as < -1.0 and < or = -2.5, was used to identify subjects with osteopenia and osteoporosis by WHO criteria. The crude prevalence of osteoporosis in radius and tibia was 8.4% and 23.3% respectively; after adjustment for age, it changed 6.3% and 18.8%. In simple logistic regression analysis, the prevalence of osteoporosis increased by aging, non-marital status, low education, low income. Otherwise, high intakes of Ca/P, thiamin, riboflavin, vitamin B6, and vitamin E were decreased osteoporosis prevalence. Compared to the normal BMI (body mass index) group (18.5 < or = BMI < 23), the odds ratio (ORs) of the low BMI group (BMI < 18.5), and high BMI groups (BMI 25 - 30, BMI > or = 30) were significantly increased. The OR of osteoporosis decreased across increasing quartiles of intakes of Ca, P and Ca/P. Therefore, maintaining normal BMI and increasing Ca intake and Ca/P ratio may have a beneficial effect on bone health of Korean women.