Analysis Regarding Effect of Sympathetic Nerves on Body Regulation and Acupuncture Efficacy by Alpha1-adrenoreceptor Mediation
10.13241/j.cnki.pmb.2017.23.048
- VernacularTitle:α1-肾上腺素受体介导交感神经对机体调节及针灸效应的研究情况分析
- Author:
Hongxin BAI
;
Bo JI
;
Guozhen ZHAO
;
Dan WANG
;
Mingna YAN
;
Xiaomin SUN
;
Yawen LU
;
Jian DAI
- Keywords:
Alpha1-AR;
Sympathetic nerve;
Blood vessel;
Central;
Acupuncture
- From:
Progress in Modern Biomedicine
2017;17(23):4597-4600
- CountryChina
- Language:Chinese
-
Abstract:
To clarify the effect of the sympathetic nerves on the body's physiopathological changes and acupuncture effect by the alphal-AR mediation in the past 30 years.The paper has referred to the database of CNKI and Pubmed,and systematically reviewed the publications in the past 30 years about the research of the alphal-AR mediation of the sympathetic nerves to the body's physiological andpathological changes and acupuncture effect.Alphal-AR not only mediated the sympathetic nerves on the inotropic change of the heart,and the contraction of the vascular smooth muscles,bladder sphincter,and uterine smooth muscles and other physiological effect,but also mediated cardiac arrhythmia,myocardial hypertrophy and other pathological process.In addition,Alphal-AR also mediated the acupuncture signal transmission,and acupuncture was able to adjust the sympathetic nervous tension.The body's physiopathological changes are closely related to alpha1-AR and subtype alteration.The in-depth study of alphal-AR helps to explain physiopathological mechanism of the body,as well as provide theoretical basis and the corresponding pharmacological models for better selective drugs.Studying Alpha1-AR on meridians contributes to the discovery of meridian essence and the substantial basis of acupuncture effects.
