The Progress of Non-invasive Screening Methods for Colorectal Cancer
10.13241/j.cnki.pmb.2017.27.050
- VernacularTitle:结直肠癌无创筛查技术研究进展
- Author:
Zucong CAO
;
Yunlong LIU
;
Bingjie ZOU
;
Yunsong WANG
;
Guohua ZHOU
- Keywords:
CRC;
Early screening;
Non-invasive;
Feces;
Blood
- From:
Progress in Modern Biomedicine
2017;17(27):5396-5400
- CountryChina
- Language:Chinese
-
Abstract:
Early detection and treatment of high-risk adenomas and colorectal cancer (CRC) can reduce mortality of this disease.CRC screening is aimed at minimizing its harm and colonoscopy is presently the gold standard for it.However,colonoscopy needs bowel preparation and is invasive with high risk of intestinal perforation,causing a bad compliance,which is unfavorable to its popularization and application.Recently,non-invasive detection methods for CRC have gone through a rapid development.Tests based on CRC-related biomarkers in fecal and blood samples provide new options for non-invasive CRC screening.However,detection methods for these biomarkers still need further research and improvement because of the complex composition of feces and blood.In the two aspects of fecal tests and blood tests,the progress of recent studies on non-invasive screening methods for CRC was reviewed in this article.