Effects of Embolization and Clipping Therapy on Cognitive Function in Patients with Intracranial Aneurysms
10.13241/j.cnki.pmb.2017.23.022
- VernacularTitle:栓塞和夹闭治疗对颅内动脉瘤患者认知功能的影响
- Author:
Gang XIAO
;
Xudong CHE
;
Xing PENG
;
Chao LUO
;
Guangyuan JIANG
- Keywords:
Intracranial aneurysm;
Endovascular intervention;
Embolism;
Cognitive function
- From:
Progress in Modern Biomedicine
2017;17(23):4498-4501,4509
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effects of endovascular embolization and microsurgical clipping on cognitive function in patients with intracranial aneurysm.Methods:A total of 80 patients with intracranial aneurysms,who were treated in Chongqing Hospital of Traditional Chinese Medicine from March 2014 to September 2015,were selected and randomly divided into control group(n=40) and experimental group (n=40).The control group was treated with microsurgical clipping,and the experimental group,with endovascular embolization.The postoperative cognitive function was assessed by the mini mental state examination scale (MMSE),and length of stay,in-hospital mortality rate,mortality rate in 1 year and the incidence of postoperative adverse reactions were compared between the two groups.Results:The total score (26.78± 0.85) of MMSE in the experimental group was higher than that (22.25± 0.63) of the control group (P＜0.05).The cognitive dysfunction rate (37.50％) of the experimental group was lower than that (55.00％) of the control group (P＜0.05).The length of stay [(6.7± 3.9) days] of the experimental group was lower than that [(9.6± 4.5) days] of the control group(P＜0.05).There were no significant differences in in-hospital mortality rate and mortality rate in 1 year,and the incidence of adverse reactions between the two groups (P＞0.05).Conclusion:Endovascular interventional therapy can improve the cognitive function of the patients with intracranial aneurysms and shorten the length of hospital stay.
