Association between early functional outcome and serum thyroid hormone level in elderly acute ischemic stroke patients
10.3969/j.issn.1009-0126.2017.09.009
- VernacularTitle:老年急性缺血性脑卒中患者早期功能预后与甲状腺功能变化的相关性
- Author:
Jinjing WANG
;
Fengli LI
;
Ruibing GUO
- Keywords:
stroke;
thyroid hormones;
thyrotropin;
prognosis
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2017;19(9):930-933
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the association between early functional outcome and serum thyroid hormone level in elderly acute ischemic stroke (AIS) patients.Methods Two hundred and twenty-four AIS patients admitted to our hospital from May to December 2016 were divided into good functional outcome group (n=166) and poor functional outcome group (n=58) according to their mRS score.The serum levels of FT3,FT4,TSH were measured.The patients were further divided into FT3≤4.05 pmol/L,FT3 4.06-4.46 pmol/L,and FT3＞4.46 pmol/L.The association between early functional outcome and serum levels of FT3,FT4,TSH in elderly AIS patients were analyzed by univariate and multivariate logistic analysis.Results The AIS was severer,the BMI and incidence of AF were higher,the number of WBC was greater,the serum FT3 and CRP levels were higher in poor functional outcome group than in good functional outcome group (P＜0.05,P＜0.01).The rate of poor functional outcome was significantly higher in FT3≤4.05 pmol/L than in FT3 4.06-4.46 pmol/L and FT3 ＞4.46 pmol/L (39.5％ vs 22.2％,39.5％ vs 15.8％,P=0.003).Univariate logistic regression analysis and multivariate logistic regression analysis showed that FT3 was an independent risk factor for early poor functional outcome in AIS patients.Concision The lower the serum FT3 level on admission is,the poorer the early functional outcome is in AIS patients.
