Analysis of the clinical effect of IPL combined with tranexamic acid in treating chloasma

VernacularTitle:光子嫩肤术联合氨甲环酸治疗黄褐斑的临床效果分析
Author: Xia LI ; Jianguo FAN
Keywords: Photochemotherapy; Tranexamic acid; Chloasma
From: Chinese Journal of Primary Medicine and Pharmacy 2017;24(20):3130-3133
CountryChina
Language:Chinese
Abstract: Objective To explore the clinical effect of IPL combined with tranexamic acid in the treatment of chloasma.Methods 50 patientss with chloasma were selected,and they were randomly divided into two groups by odd-and-even grouping method.The control group received IPL treatment,the study group was given photorejuvenation combined with tranexamic acid treatment.The MASI score,clinical efficacy and adverse reactions were compared between the two groups.Results The MASI score[(8.71 ± 0.82) points] and the total effective rate (92.00％) of the study group were significantly better than those of the control group [(11.35 ± 1.03) points,68.00％,t =3.10,x2 =4.39,all P ＜ 0.05].The incidence rate of adverse reaction betweem the two groups (16.00％,16.00％) had no significant difference (x2 =0.00,P ＞ 0.05).Conclusion Photorejuvenation combined with tranexamic acid has significant clinical effect in the treatment of chloasma.