Application of mesangial thyroid resection in papillary thyroid carcinoma with central lymph node dissection and its influence on postoperative recurrence
10.3760/cma.j.issn.1008-6706.2017.20.037
- VernacularTitle:甲状腺系膜切除术在甲状腺乳头状癌中央区淋巴结清扫中的应用及对术后复发的影响
- Author:
Haiyan HUANG
;
Bin LU
- Keywords:
Thyroid neoplasms;
Neck dissection;
Recurrence
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(20):3175-3178
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application of mesangial thyroid resection in papillary thyroid carcinoma(PTC) with central lymph node dissection,and its influence on postoperative recurrence.Methods 76 cases with PTC were divided into two groups according to random number table,each group in 38cases.The control group was given primary lesions radical prostatectomy and routine central lymph node dissection,the treatment group was given primary lesions radical prostatectomy and central lymph node dissection by thyroid mesangial resection.The parathyroid function,injury of recurrent laryngeal nerve and local recurrence were compared between the two groups.Results Compared with before surgery,the levels of serum PTH and blood calcium were significantly decreased at the 1st,3rd day after surgery (all P < 0.05),while there were no statistically significant differences in serum PTH and blood calcium at the 7th day after surgery(all P >0.05).The levels of serum PTH and blood calcium at the lst,3rd,7th day after surgery between the two groups had no statistically significant differences(all P < 0.05).The incidence rate of injury of recurrent laryngeal nerve in the treatment group was significantly lower than that in the control group (5.3% vs.21.1%,x2 =4.15,P < 0.05).The secondary surgery rate and local recurrence within 2 years in the treatment group were significantly lower than those in the control group (0% vs.15.8%,2.6% vs.18.4%,x2 =6.51,4.69,all P < 0.05).Conclusion Primary lesions radical prostatectomy and central lymph node dissection by thyroid mesangial resection can be used as theroutine operation for PTC,which can effectively produce complete dissection,reduce injury of recurrent laryngeal nerve and local recurrence.