Research progress of establishing cardiomyocytedisease models by human induced pluripotent stem cells
- VernacularTitle:人诱导性多潜能干细胞建立心肌细胞疾病模型的研究进展
- Author:
Ning CUI
;
Lei LI
;
Ming CUI
;
Feng LAN
- Keywords:
induced pluripotent stem cell;
cardiomyocyte disease model;
research progress
- From:
Basic & Clinical Medicine
2017;37(9):1331-1335
- CountryChina
- Language:Chinese
-
Abstract:
Induced pluripotent stem cell is a landmark in the stem cell study field, which has rapidly developed in the past 10 years.By obtaining induced pluripotent stem cells from somatic cell, and then differentiating into cardiomyocyte, various cardiomyocyte disease models could be established,which can be used for research of disease mechanisms, drug screening and gene therapy.This review introduces the successfully established cardiomyocyte disease models from human induced pluripotent stem cells, and points out the problems and prospects.
