Research on the relationship between mucoepidermoid carcinoma and human papillomavirus infection
10.16066/j.1672-7002.2017.05.005
- VernacularTitle:腮腺黏液表皮样癌与人乳头瘤病毒感染的相关性研究
- Author:
Shiyan CHEN
;
Hongxun GONG
;
Maoxin WANG
;
Xianming CHEN
- Keywords:
Parotid Neoplasms;
Carcinoma Mucoepidermoid;
Human Papillomavirus
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2017;24(5):237-238
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To find out the relationship between mucoepidermoid carcinoma and Human papillomavirus (HPV) infection.METHODS Nested polymerase chain reaction (Nested PCR) was adapted to detect HPV DNA from 51 tissues of mucoepidermoid carcinoma using consensus primers, 9 tissues of chronic parotitis were as control.RESULTS HPV DNA was detected in 37 of total 51 mucoepidermoid carcinoma tissues, the detection rate was up to 72.5%, comparatively, it was 22.2% (2 of 9) in chronic parotitis tissues. The HPV DNA detection rate of mucoepidermoid carcinoma tissues was statistically higher than that of chronic parotitis tissues (χ2=8.517, P=0.004).CONCLUSION The results suggested that the HPV infection may cause mucoepidermoid carcinoma.
