Relationship between adiponectin and diabetic retinopathy
10.3760/cma.j.issn.1005-1015.2017.03.029
- VernacularTitle:脂联素与糖尿病视网膜病变相关性研究现状
- Author:
Yunyun LI
;
Ningpu LIU
- Keywords:
Diabetic retinopathy/etiology;
Adiponectin;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2017;33(3):324-327
- CountryChina
- Language:Chinese
-
Abstract:
The exact pathophysiological mechanisms of diabetic retinopathy (DR) remain elusive.The inflammatory reaction,retinal vascular leakage and retinal neovascularization are main features of DR.Adiponectin (APN) is an endogenous biological active protein secreted by adipocytes.It can increase insulin sensitivity,regulate blood glucose and lipid metabolism,and has anti-inflammation and anti-neovascularization functions.It may be involved in the development of DR.This review summarized the studies on the association between APN and DR in recent years.
