A Case of Achieving Complete Remission with Combination of Stereotac-tic Body Radiation Therapy and Transarterial Chemoemoblization in Pa-tients with 4.8 cm Sized Infiltrative Hepatocellular Carcinoma with Arte-riovenous Shunt.
- Author:
Sang Youn HWANG
1
;
Seon Mi LEE
;
Jung Woo IM
;
Joon Suk KIM
;
Ki Jeong JEON
;
Sang Bu AHN
;
Eun Kyeong JI
;
Hyun Cheol KANG
;
Cheol Won CHOI
;
Gwang Mo YANG
Author Information
1. Department of Internal Medicine, Dongnam Institute of Radiological & Medical Sciences, Busan, Korea. mongmani@hanmail.net
- Publication Type:Case Report
- Keywords:
Infiltrative hepatocellular carcinoma;
Arteriovenous shunt;
Stereotactic body radiation therapy;
Transarterial chemoembolization
- MeSH:
Carcinoma, Hepatocellular*;
Humans;
Prognosis
- From:Journal of Liver Cancer
2015;15(1):64-69
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Infiltrative hepatocellular carcinoma (HCC) patients have a poor prognosis because most patients present with advanced disease. Although tumor size is small, ablation therapy is difficult because it is difficult to delineate tumor boundary and tumor often combined vascular invasion. Therefore many clinicians still try locoregional therapy (LRT) such as transarterial chemoembolization (TACE), radiation therapy (RT), or combination with LRT and sorafenib in this situation. Stereotactic body radiation therapy (SBRT) is new technology providing very highly conformal ablative radiation dose and is expected to salvage modality for HCC showed incomplete response of TACE due to combined arteriovenous (AV) shunts. Based on above suggestions, we herein offer our experience of a complete remission of tumor by combination of SBRT and TACE in a patient with infiltrative HCC. Further study, maybe regarding a combination of locoregional and systemic therapy is necessary on how to manage infiltrative HCC with AV shunts.
