Retrospective analysis of 18 cases of anaphylactic shock induced by bupleurum injection

VernacularTitle:柴胡注射液过敏性休克18例回顾性分析
Author: Lei ZHANG
Keywords: Anaphylaxis; Shock; Bupleurum Injection; Retrospective Studies
From: Chinese Journal of Primary Medicine and Pharmacy 2017;24(18):2776-2779
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinic features and regularity of anaphylactic shock induced by bupleurum injection,and to provide reference in clinic tor rational use of bupleurum injection.Methods Checked out the case reports of anaphylactic shock induced by bupleurum injection in the data-bases in China from 1996 to 2015 for statistics and analysis.Results 18 cases of anaphylactic shock were reported and sexual equality,and all were injected intramuscularly;13 cases (72.2％) occurred within 5min and cardiovascular system and central nervous system as the main clinical manifestations.By the active anti-shock therapy,17 cases recovered and 1 case died.Conclusion Allergic shock induced by bupleurum injection happens now and then in clinics,so clinical drug using should pay attention to the history of allergies and medication adverse reactions in the process of observation,in order to reduce drug safety hazards.