Analysis on the correlation of plasma D-dimer level with chronic obstructive pulmonary disease

VernacularTitle:血浆D-二聚体水平与慢性阻塞性肺疾病急性加重期的相关性分析
Author: Shuang FENG ; Lan YANG ; Yong JIN ; Yanli HAN
Keywords: D-dimer; Pulmonary disease,chronic obstructive
From: Chinese Journal of Primary Medicine and Pharmacy 2017;24(18):2812-2814
CountryChina
Language:Chinese
Abstract: Objective To investigate the correlation between the D-dimer level and the acute exacerbation of chronic obstructive pulmonary disease (AECOPD).Methods The changes of D-dimer levels in 156 patients (AECOPD group) before and after treatment were measured and compared with the D-dimer levels of 156 healthy subjects(control group).Results The concentration of plasma D-dimer in the AECOPD group was (1.35 ± 1.46) mg/L,which was significantly higher than (0.25 ± 0.16)mg/L in the control group,and the difference was statistically significant(t =9.354,P ＜0.05).The level of plasma D-dimer in the AECOPD group was (0.69 ± 0.87)mg/L,and compared with (1.35 ± 1.46)mg/L before treatment,the difference was statistically significant(t =4.850,P ＜ 0.05).Conclusion D-dimer level is correlated to the condition of patients with chronic obstructive pulmonary disease,it can be used as one of the indicators to diagnose whether a patient is in hypercoagnlable state or suffers thrombotic diseases.