Application of statins in prevention and treatment of liver diseases
10.3969/j.issn.1001-5256.2017.05.041
- VernacularTitle:他汀类药物在肝病防治中的应用
- Author:
Lu LIU
;
Tao HAN
;
Lengxiao ZHOU
- Keywords:
liver diseases;
hydroxymethylglutaryl-CoA reductase inhibitors;
review
- From:
Journal of Clinical Hepatology
2017;33(5):985-989
- CountryChina
- Language:Chinese
-
Abstract:
Statins are widely used as important lipid-lowering drugs,and studies have proven the safety of statins in patients with liver diseases.In recent years,there have been more and more studies on the effects of statins in the prevention and treatment of hepatitis C,fatty liver disease,liver cirrhosis,and hepatocellular carcinoma.Studies have shown that besides the lipid-lowering effect,statins also have various other effects,including anti-inflammatory effect,immune regulation,anti-proliferation,and antioxidant effect,and they can also improve vascular endothelial function and inhibit platelet aggregation.Their roles in the prevention and treatment of liver diseases await further research.
