Extraction Process of Yinxing Huonao Capusle by Central Composite Design-Response Surface Method
10.3870/j.issn.1004-0781.2017.06.017
- VernacularTitle:中心组合设计-响应面法优化银杏活脑胶囊的提取工艺
- Author:
Lijun QI
;
Hongen QIN
;
Huabin HUANG
- Keywords:
Yinxing Huonao capusle;
Central composite design-response surface methodology;
Extraction process
- From:
Herald of Medicine
2017;36(6):668-672
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the extraction process of Yinxing Huonao capusle.Methods Central composite design-response surface method was used to optimize the extraction process with quantity of water and boiling time as main factors and with syringin transfer rate,emodin transfer rate and solids retention rate as evaluation index.Results The conditions of the optimized extraction process were as follows:10-fold water,extracting time of 160 min,extracting 2 times.Conclusion It is feasible that central composite design-response surface method is used to optimize the extraction process of Yinxing Huonao capusle,and the optimized extraction process is simple and reliable.