Observation of the clinical effect of sodium hyaluronate combined with glucocorticoid on the treatment of periarthritis of shoulder
10.3969/j.issn.1005-1678.2017.05.024
- VernacularTitle:玻璃酸钠联合糖皮质激素治疗肩周炎的疗效观察
- Author:
Hao LUO
;
Yi YUAN
;
Chao YANG
- Keywords:
sodium hyaluronate;
glucocorticoid;
periarthritis of shoulder;
joint mobility
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(5):77-79
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of sodium hyaluronate combined with glucocorticoid on the treatment of periarthritis of shoulder.Methods106 patients in department of orthopedics, the second hospital of Ningbo with periarthritis of shoulder were randomly divided into 2 groups (n=53).The control group were treated with anti-inflammatory and analgesic treatment, at this basis, the study group were treated with sodium hyaluronate combined with Glucocorticoid.5 weeks for a course of treatment.Levels of serum inflammation, laboratory-related indicators were compared.ResultsCompared with before treatment, shoulder joint activity in the two groups increased, VAS score decreased, the scores of strength of shoulder joint, range of motion and daily activities increased, levels of serum IL-6, IL-10, TNF-α decreased(P<0.05).Compared with the control group, scores of activity in the study group were higher, VAS scores were lower, scores of strength of shoulder joint, range of motion and daily activities were higher, levels of serum IL-6, IL-10, TNF-α were lower(P<0.05).The effective rate in the control group(73.59%) was lower than the study group(90.57%), but there was no statistical difference.ConclusionThe effect is accurate which sodium hyaluronate combined with glucocorticoid was used in the treatment of periarthritis of shoulder, and it can reduce the inflammation index and improve the joint activity.
