Effect of liver detoxification soup combined with compound glycyrrhizin on hepatitis related factors in patients with chronic hepatitis B
10.3969/j.issn.1005-1678.2017.05.043
- VernacularTitle:化肝解毒汤联合复方甘草酸苷对慢性乙肝患者血清肝炎相关因子水平的影响
- Author:
Fang WU
;
Lemei DONG
;
Xiaowei CHEN
;
Wei WU
- Keywords:
liver detoxification soup;
compound glycyrrhizin;
chronic hepatitis B;
Hepatitis-related factor
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(5):131-133
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of liver detoxification soup combined with compound glycyrrhizin on hepatitis-related factors in patients with chronic hepatitis B.MethodsFrom April 2014 to August 2015, 86 patients with chronic hepatitis B were enrolled in this study.Random number table was divided into observation group and control group (43 cases).The control group was given routine glycyrrhizin and other conventional (ALT), serum total bilirubin (TBil), serum albumin transferase (ALT) and serum total bilirubin (TBil) were measured before and after treatment.(HA), laminin (LN), type Ⅳ collagen (Ⅳ-C) and type Ⅲ procollagen (PCⅢ) were used to analyze the effect of hepatic fibrosis, And observe adverse reactions.ResultsThe effective rate of the observation group was 93.02% higher than that of the control group (76.74%, P<0.05).After treatment, the patients were treated with chest discomfort, emotional depression, epigastric fullness, fatigue, ALT (35.28±1.35) U/L, HA (165.25±1.44) mg/L, and the treatment group (P<0.05).After treatment, the levels of TBil (30.34±1.59)μmol/L, Alb (48.32±1.33)g/L, and the level of serum was significantly higher than that of the control group (P<0.01).The incidence of adverse reactions was 11.63% and 6.98% in the two groups.ConclusionTraditional Chinese medicine hepatectomy decoction combined with compound glycyrrhizin can effectively treat chronic hepatitis B and improve the level of serum hepatitis-related factors, and the adverse reaction is light, it is worthy of clinical application.
