Clinical and CT identification between preinvasive and invasive lung adenocarcinoma presented as pure ground-glass opacity

VernacularTitle:纯磨玻璃密度浸润前病变与浸润性肺腺癌的临床及CT鉴别
Author: Yuqiang ZUO ; Qingchun MENG ; Yunxia TIAN ; Xiaoling ZUO ; Xiaohui QIAO ; Qing QIAO ; Liang ZHAO
Keywords: lung neoplasms; adenocarcinoma; ground-glass opacity; tomography,X-ray computed
From: Chongqing Medicine 2017;46(13):1782-1785
CountryChina
Language:Chinese
Abstract: Objective To investigate the diffevential diagnostic value of preinvasive and invasive lung adenocarcinoma (including minimally invasive adenocarcinoma and invasive adenocarcinoma) presented as pure ground-glass nodules(pGGN) by CT.Methods One hundred and fifty-six cases of pGGN verified by operative pathology were retrospectively analyzed,including 58 ca ses of preinvasive adenocarcinoma and 98 cases of invasive adenocarcinoma(TNM staging were T1N0M0).The CT features and sex were statistically processed.The difference between the CT features and sex were performed by thex2 test.The ROC curve of lesion focus size was drawn.Results Statistically significant differences were found in the lesion shape,vacuole sign,air bronchogram,blood vessel through,tumor-lung interface and vascular cluster sign between the two groups(all P＜0.05).The ROC curve showed that the accuracy rate of invasive adenocarcinoma was 75.0％ when the size of the pGGN lesions was larger than 15.35 mm.Conclusion The lesion size,shape,vacuole sign,air bronchogram,blood vessels through and vascular cluster sign have some predictive value.