Early predictive factors for intestinal necrosis in acute superior mesenteric artery occlusive diseases
10.3760/cma.j.issn.1007-631X.2017.04.005
- VernacularTitle:急性肠系膜上动脉闭塞性疾病发生肠坏死的早期预测因素
- Author:
Dafang LIU
;
Xiaoqiang HAO
;
Yingjiang YE
;
Qiwei XIE
;
Mujun YIN
;
Xiaodong YANG
;
Bin LIANG
;
Shan WANG
- Keywords:
Mesenteric vascular occlusion;
Mesenteric artery,superior;
Forecasting;
Intestinal necrosis
- From:
Chinese Journal of General Surgery
2017;32(4):301-305
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the early predictive factors of intestinal necrosis in patients with acute superior mesenteric arterial occlusive disease and its significance for the decision of exploratory laparotomy.Methods This retrospective study enrolled 29 patients diagnosed with acute superior mesenteric artery embolism or thrombosis in Peking University People's Hospital between July 1995 and June 2015.Results 12 patients developed intestinal necrosis.Patients with intestinal necrosis had a poorer prognosis than those who did not develop intestinal necrosis (x2 =14.867,P =0.000).In univariate analysis,the early predictive factors for intestinal necrosis were D-Dimer ≥ 600 μg/L (x2 =11.455,P =0.002),INR≥1.2 (x2 =3.948,P =0.047),pH values ＜7.4 (x2 =8.191,P =0.004),BE ＜ -1.0 mmol/L (x2 =8.191,P =0.004),blood lactate ≥ 2.2 mmol/L(x2 =7.535,P =0.006),BUN ≥ 6 mmol/L (x2 =10.076,P =0.002),CK ≥ 80 U/L (x2 =8.191,P =0.004),LDH ≥ 210 U/L (x2 =13.079,P=0.000),AST ≥25 U/L (x2 =10.076,P =0.002),SIRS (x2 =10.076,P =0.002).Multivariate logistic regression analysis found no independent predictive factors of intestinal necrosis in patients with acute superior mesenteric arterial occlusive diseases.Conclusion Intestinal necrosis in acute mesenteric arterial occlusive diseases indicates a poor prognosis.Coagulation abnormalities,liver or kidney dysfunction,metabolic acidosis and SIRS necessitates an immediate exploration.
