Sexual chromosome in patients with unclear gender indentification at the national institute of hematology and blood transfusion (1996-2005)
- Author:
Vinh Quang Pham
;
Thuy Thi Kieu
- Publication Type:Journal Article
- Keywords:
sexual chromosome;
malformation of enternal sexual organ
- MeSH:
Sex Chromosomes;
Gender Identity;
- From:Journal of Medical Research
2007;47(1):9-13
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Background: Normally, gender of human is indentified according to enternal sexual organ. However in several cases the patient\u2019s gender is not able to identify based on enternal sexual organ. In these cases test for gender identification is need. Objectives: Identify relationship between clinical condition of the external sexual organ and sexual chromosome. Subjects and method: 119 patients with diagnosis of \u201cunclear gender identification\ufffd?made by hospitals in Ha noi. Culture of peripheral blood, analyze sexual chromosome, comparing with gender indentification proposed in neonatal period and gender indentified by physical at time of examination. Results: 87/119 cases (73,11%) have male sexual chromosome. According of gender proposed in neonatal period to sexual chromosome are 76,90% for children considered \u201cboy\ufffd?and only 33,33% for \u201cgirl\ufffd? The according percentage is higher at time of examination (mean age is 6,4 years old). There are 4 cases of female phenotype with XY sexual chromosome. Conclusion: In cases with unclear gender identification in neonatal period: 73,11% cases have male sexual chromosome (XY). Apprasal gender at neonatal period is difficulty accurate, especialy for children considered girl (the according rate is only 33,33%). \ufffd?Detect 4 cases of \u201ctesticular femiuization\ufffd?
