Research advances in polyphenols scavenging endogenous formaldehyde
10.3867/j.issn.1000-3002.2017.06.015
- VernacularTitle:多酚类化合物清除内源性甲醛的作用及其机制研究进展
- Author:
Anqi SUN
;
Haipeng JIANG
;
Xiulian JU
- Keywords:
formaldehyde,endogenous;
polyphenols;
cardiovascular diseases;
cerebrovascular diseases;
metabolism
- From:
Chinese Journal of Pharmacology and Toxicology
2017;31(6):597-606
- CountryChina
- Language:Chinese
-
Abstract:
Endogenous formaldehyde is generated in the human body.When the system of endogenous formaldehyde generation with scavengation is damaged,excess accumulation of endogenous formaldehyde induces vascular endothelial injury,atherosclerosis,myocardial damage and neurodegenerative diseases.Studies show that endogenous formaldehyde is one of the key factors during the process of cardiovascular and cerebrovascular diseases.Moreover,polyphenols are used as capture agents of endogenous formaldehyde to prevent and treat cardiovascular and cerebrovascular diseases.
