Observation on the influence of ademetionine for the proteometabolism and fibrosis indexes of patients with chronic hepatitis B
10.3969/j.issn.1005-1678.2017.05.017
- VernacularTitle:腺苷蛋氨酸对慢性乙型肝炎患者蛋白代谢及纤维化指标的影响观察
- Author:
Yifang CHEN
;
Lanxiang HE
;
Linlin QIU
- Keywords:
ademetionine;
chronic hepatitis B;
proteometabolism indexes;
fibrosis indexes
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(5):58-60
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the influence of ademetionine for the proteometabolism and fibrosis indexes of patients with chronic hepatitis B.Methods110 patients with chronic hepatitis B in our hospital from January to December 2016 were randomly divided into control group(conventional treatment of hepatitis B group)55 cases and observation group(conventional treatment and ademetionine group)55 cases.The serum expression levels of proteometabolism and fibrosis indexes of two groups before the treatment and after the treatment were detected and compared.ResultsThe serum expression levels of proteometabolism and fibrosis indexes of two groups before the treatment were compared,there were no significant differences,while the serum expression levels of proteometabolism indexes of observation group after the treatment were all higher than those of control group,the serum expression levels of fibrosis indexes were all lower than those of control group,there were all significant differences(all P<0.05).ConclusionThe ademetionine can significantly improve the expression state of proteometabolism and fibrosis indexes of patients with chronic hepatitis B,so the application value for the patients with chronic hepatitis B is relatively higher.
