Effects of Xuesaitong and Danhong injection on acute cerebral infarction and the effects of serum bilirubin and uric acid
10.3969/j.issn.1005-1678.2017.05.036
- VernacularTitle:血塞通与丹红注射液联合用药对急性脑梗死患者的疗效及血清胆红素与尿酸水平影响的比较研究
- Author:
Ru SUN
;
Dongwei ZHANG
;
Xu ZHANG
- Keywords:
Donhong injection;
acute cerebral infarction;
clinical curative effect;
blood uric acid;
bilirubin
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(5):110-112
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the comparison of blood uric acid and bilirubin levels on patients with acute cerebral infarction and the clinical curative effect of Donhong injection.MethodsA total of 68 patients with acute cerebral infarction from our hospital neurology, according to different therapeutic methods were divided into control group and experimental group with 34 cases in each group, two groups were treated by conventional treatment, patients in the control group were treated by blood flux injection 400 mg+5% glucose injection 250 mL intravenous drip, once a day;patients in the experimental group were treated by Dan red injection 40 mL+5% glucose injection 250 mL intravenous drip, once a day,2 groups of patients were treated for 2 cycles,a cycle with 7 d.Compared the clinical efficacy, blood uric acid, bilirubin, blood homocysteine, hyperensitive C-reactive protein, serum inhibition C and adverse reactions in the two groups after treatment.ResultsCompared with the control group, the experimental group clinical total effective rate was higher after treatment (P< 0.05).Compared with the control group, the experimental group blood uric acid, blood homocysteine, hypersensitive C-reactive protein, serum inhibition C levels were lower (P< 0.05), bilirubin level was higher(P< 0.05).Adverse reactions compared between the two groups, there was no statistically significant difference.ConclusionDonhong injection in the treatment of acute cerebral infarction clinical curative effect is distinct, dacrease blood uric acid level and increase bilirubin level, improve endothelial cell damage, protect the brain tissue.
