Influences of Shendan Sanjie capsule on chemotherapy effect and immune index to patients with advanced non-small cell lung cancer
10.3969/j.issn.1005-1678.2017.05.065
- VernacularTitle:参丹散结胶囊对晚期非小细胞肺癌患者化疗疗效及免疫的影响分析
- Author:
Zhejiong WANG
;
Xingsheng BU
;
Panli TAN
;
Juqin SUN
- Keywords:
Shendan Sanjie capsule;
non-small cell lung cancer;
chemotherapy;
immune
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(5):200-202
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the influences of Shendan Sanjie capsule on chemotherapy effect and immune index to patients with advanced non-small cell lung cancer.MethodsDividing 76 patients with advanced non-small cell lung cancer from department of oncology from January 2014 to May 2016,each with 38 cases.The control group recei-ved western chemotherapy,observation group received western chemotherapy with Shendan Sanjie capsule.The differences of related indicators were compared.Results①After chem-otherapy,in the control group, CD4+decreased,CD8+ increased and CD4+/CD8+ decreased,and before chemotherapy, the difference was significant(P<0.05).In observation group,there was no significant difference in CD4+, CD8+, CD4+ / CD8+ levels.The above indicators of observation group were better than that of control group.②After chemotherapy,RR(CR+PR)rate of observation group were 57.89%, higher than the control group with 36.84%(P<0.05).③During chemotherapy,toxic side effect ratio of observation group was lower than that of the control group(P<0.05).ConclusionComparing Shen Dan Sanjie capsule can adjust patient immunity and reduce side effects of chemotherapy during chemotherapy.
