Clinical effects of Sini powder combing with enema in treatment of chronic nonspecific ulcerative colitis
10.3969/j.issn.1005-1678.2017.05.070
- VernacularTitle:四逆散联合灌肠保守治疗慢性非特异性溃疡性结肠炎的临床研究
- Author:
Kangming ZHU
;
Chenghao CHEN
- Keywords:
Sini powder;
enema;
chronic nonspecific ulcerative colitis;
inflammation;
recurrence rate
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(5):214-216
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research clinical effects of Sini powder combing with enema in treatment of chronic nonspecific ulcerative colitis.Methods132 patients with chronic nonspecific ulcerative colitis treated in our hospital from January 2015 to October 2016 were randomly divided into two groups,with 66 cases in each group.The control group was treated with enema,and observation group was treated with Sini powder combing with enema to analyse effect of Sini powder.Results①The total effective rate was 93.94% in the observation group,higher than control group 75.76%(P<0.05).②After treatment,serum CRP,IL-8 and TNF-ɑ level of observation group were (14.92±3.04)mg/L、(0.52±0.05)μg/L、(18.65±3.18)ng/L,lower than control group(23.04±3.31)mg/L、(0.75±0.08)μg/L、(25.59±3.62)ng/L(all P<0.05).③ ESR and PLT level of observation group were(11.16±2.27)mm/h、(220.6±15.8)×10.9/L,lower than control group(15.93±2.58)mm/h、(258.3±18.9)×10.9/L(all P<0.05).④The adverse reaction rate was 15.15% in the observation group,and 21.22% in the control group, the difference was not statistically significant.⑤ The recurrence rate was 23.81% in the observation group,lower than control group 39.06%(P<0.05).ConclusionSini powder can improve the effect in treatment of chronic nonspecific ulcerative colitis and has higher security.
