Efficiency comparison of Esomeprazole and Omeprazole in the treatment of gastric ulcer
10.3969/j.issn.1005-1678.2017.05.076
- VernacularTitle:埃索美拉唑与奥美拉唑治疗胃溃疡的疗效比较
- Author:
Wei ZHANG
;
Xuetian XU
;
Fan YANG
- Keywords:
Esomeprazole;
Omeprazole;
gastric ulcer;
clinical efficacy
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(5):232-233
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficacy of esomeprazole and omeprazole in the treatment of gastric ulcer, and to provide a reference for the clinical treatment of gastric ulcer.Methods80 cases of gastric ulcer patients in our hospital from February to April 2014 were randomly divided into observation group and control group, with 40 cases in each group.The patients in the control group were treated with omeprazole,the patients in the observation group were treated with Esomeprazole, patients received three courses of treatment,the changes of body after treatment in two groups were observed, the degree of stomach pain and the changes of the condition were analyzed, the healing degree of gastric ulcer was observed, the clinical therapeutic effect of two groups was analyzed.ResultsAfter treatment, the recovery rate of the observation group was 100%, significantly higher than the control group 90%, the difference was statistically significant (P<0.05).The scores of pain in the observation group and the drug use score were significantly lower than those in the control group (P<0.05).The adverse reaction rate of the observation group was significantly lower than that of the control group, the difference was statistically significant (P<0.05).ConclusionThe efficiency of Esomeprazole in the treatment of gastric ulcer is better than omeprazole, patients with high satisfaction, can effectively shorten the wound healing time, reduce patient treatment time, reduce medical costs, and adverse reactions light.
