The relationship between female anti-sperm immune infertility and chronic inflammation in female reproductive tract
10.3969/j.issn.1005-1678.2017.05.080
- VernacularTitle:女性抗精子免疫性不孕与慢性生殖道炎症的相关性研究
- Author:
Hao YUAN
- Keywords:
anti-sperm immune infertility;
chronic inflammation in female reproductive tract;
clinical effect;
antibiotic.
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(5):243-245
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate relationship between anti-sperm immune infertility and chronic inflammation in female reproductive tract.Methods80 patients of anti-sperm immunity infertility were selected, and randomly divided into the study group and the control group.The study group was treated with dexamethasone+Vitamin E+Vitamin C+roxithromycin, the control group was treated with dexamethasone+vitamin E+vitamin C, After a course of treatment, serum IL-6, TNF-α and the AsAb in serum and cervix change was detected before and after treatment.ResultsThe clinical efficacy of study group was significantly better than the control group, with statistical significance (P<0.05).the AsAb in serum and cervix in the study group was significantly lower than the control group, with a statistically significant difference (P<0.05).serum IL-6, TNF-α in the study group was significantly lower than the control group, with significant difference (P<0.05).ConclusionThe female anti-sperm immune infertility and the chronic inflammation in female reproductive tract are relational, The female anti-sperm immune infertility combined with antibiotic has a significant effect.