The relationship between female anti-sperm immune infertility and chronic inflammation in female reproductive tract

VernacularTitle:女性抗精子免疫性不孕与慢性生殖道炎症的相关性研究
Author: Hao YUAN
Keywords: anti-sperm immune infertility; chronic inflammation in female reproductive tract; clinical effect; antibiotic.
From: Chinese Journal of Biochemical Pharmaceutics 2017;37(5):243-245
CountryChina
Language:Chinese
Abstract: Objective To investigate relationship between anti-sperm immune infertility and chronic inflammation in female reproductive tract.Methods80 patients of anti-sperm immunity infertility were selected, and randomly divided into the study group and the control group.The study group was treated with dexamethasone+Vitamin E+Vitamin C+roxithromycin, the control group was treated with dexamethasone+vitamin E+vitamin C, After a course of treatment, serum IL-6, TNF-α and the AsAb in serum and cervix change was detected before and after treatment.ResultsThe clinical efficacy of study group was significantly better than the control group, with statistical significance (P<0.05).the AsAb in serum and cervix in the study group was significantly lower than the control group, with a statistically significant difference (P<0.05).serum IL-6, TNF-α in the study group was significantly lower than the control group, with significant difference (P<0.05).ConclusionThe female anti-sperm immune infertility and the chronic inflammation in female reproductive tract are relational, The female anti-sperm immune infertility combined with antibiotic has a significant effect.