Clinical efficacy of levosimendan injection in the treatment of patients with acute decompensated heart failure
10.3969/j.issn.1005-1678.2017.05.087
- VernacularTitle:左西孟旦注射液治疗急性失代偿性心力衰竭患者的临床疗效
- Author:
Zhaohui JI
;
Xiaohong WEN
;
Zhuquan DAI
;
Huibin PAN
- Keywords:
levosimendan injection;
acute decompensated heart failure;
dobutamine
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(5):263-265
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy of levosimendan injection in the treatment of patients with acute decompensated heart failure.Methods70 patients with acute decompensated heart failure patients were selected from January 2016 to January 2017 in huzhou first people's hospital.35 cases of patients in control group were treated with levosimendan injection, and the other 35 cases of patients in experimental group was treated with dobutamine.BNP, 24 hourly urine volume, LVEF and SV were detected and the systemic clinical conditions were assessed both before and after the treatment.ResultsAfter treatment, all indexes of two groups were better than before(P<0.05).The extent of improvement of systemic symptoms and relevant indicators such as BNP, 24 hourly urine, LVEF and SV in experimental group was larger than that in control group (P<0.05).Adverse reaction rate of experimental group was 16.7%, and adverse reaction rate of control group was 43.8%, the differences were statistically significant (P<0.05).ConclusionLevosimendan injection can relieve symptoms of patients with acute decompensated heart failure,and it has less adverse reactions.
