Clinical effect of budesonide combined with ambroxol in the treatment of neonatal aspiration pneumonia
10.3969/j.issn.1005-1678.2017.05.093
- VernacularTitle:布地奈德联合氨溴索治疗新生儿吸入性肺炎的疗效
- Author:
Heping YAO
- Keywords:
aspiration pneumonia;
newborn;
budesonide;
ambroxol
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(5):280-282
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of budesonide combined with ambroxol in the treatment of neonatal aspiration pneumonia.MethodsFrom January 2015 to January 2016 in our hospital 64 cases with neonatal aspiration pneumonia were randomly divided into two groups.The control group was treated with routine treatment, the study group used budesonide treatment, the treatment results were compared between the two groups.ResultsThe disappearance time of dyspnea, cyanosis, pulmonary rales and other symptoms and hospitalization time in study group were significantly shorter than those in the control group (P<0.01);the levels of interleukin(IL)-6, IL-8 and tumor necrosis factor alpha(TNF-α)in the study group after intervention were significantly lower than those in the control group (P<0.05) before treatment, PCT levels in two groups before treatment had no significant difference, three days, seven days and 14 days after the treatment PCT of the study group was significantly lower than the control group (P<0.05).ConclusionInhalation of budesonide and ambroxol in the treatment of neonatal pneumonia, can significantly improve the therapeutic effect, reduce the levels of inflammatory factors in children,can help the recovery of children.
