Effect of atorvastatin on efficacy and cardiovascular events in patients with unstable angina pectoris
10.3969/j.issn.1005-1678.2017.05.107
- VernacularTitle:阿托伐他汀对不稳定型心绞痛患者的疗效及心血管事件的影响
- Author:
Chen ZHANG
;
Yong ZHENG
- Keywords:
unstable angina;
atorvastatin;
cardiovascular events;
blood lipids
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(5):318-320
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of atorvastatin on the curative effect and cardiovascular events in patients with unstable angina pectoris.Methods128 patients with UAP were enrolled in Jinhua Central Hospital from August 2014 to August 2016, and 128 patients with UAP were randomly divided into observation group and control group.All the patients were given low salt and low fat diet.Two groups of patients were anti-platelet aggregation, blood pressure, lipid-lowering and other conventional treatment, observation group on the basis of simultaneous atorvastatin calcium 40mg/d, oral, once every month.The levels of TC, TG and LDL-C, HDL-C and the incidence of cardiovascular events were compared between the two groups before and after treatment.ResultsThere was no case of cardiac death in the observation group and the control group.The incidence of cardiovascular events in the observation group was 9.38%, which was significantly different from that in the control group (P<0.05).The levels of TC, TC and LDL-C in the observation group were significantly higher than those before treatment and control group, respectively.The clinical effect of the observation group was significantly better than that of the control group, the difference was significant (P<0.05).ConclusionAtorvastatin can significantly improve the efficacy of unstable angina treatment, and reduce blood lipid levels, reducing the incidence of cardiovascular events, improve the prognosis.
