Correlation analysis of bacterial resistance and antibiotic consumtion in our hospital
10.3969/j.issn.1005-1678.2017.05.135
- VernacularTitle:细菌耐药率与抗菌药物使用情况的相关性分析
- Author:
Chunlin YANG
;
Hongbo WANG
;
Jing LI
;
Lijun ZHU
;
Jianbo JIN
;
Sunjie JIN
;
Zhewen LU
- Keywords:
bacterial resistance;
antibiotics;
rational drug use
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(5):399-402
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the drug resistance of bacteria clinically isolated from Yuyao people's hospital and its relationship with antibiotic consumption, in order to provide basis for rational use of antibiotics in clinic.MethodsA total of 3178 strains of bacteria were detected in our hospital from the third quarter of 2015 to the second quarter of 2016.The drug resistance of bacteria, the consumption of antibacterial agents in each quarter, and their relationships were analyzed.ResultsThe major isolated bacteria was gram-negative bacteria, among which constituent ratio of Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa ranked the top 4.Gram-negative bacteria's resistance rates of several antibiotics were positively correlated with the utility rate of quinolones, and also had a different degree of positive correlation with the use of beta lactamase/inhibitor, aminoglycosides and carbapenems.Staphylococcus were the mainly gram positive bacteria, whose resistance rates to penicillin, ciprofloxacin, levofloxacin and erythromycin were positively correlated with the usage of the same type of antibiotics.ConclusionBacterial resistance rates are closely associated with the consumption of antimicrobials.Selecting antibacterial agents reasonably according to the results of drug susceptibility test is important to control the drug resistance of bacterial.
