New discoveries about the role of SREBPs in the pathogenesis and targeted therapy of gynecological tumors
10.3760/cma.j.issn.1008-6315.2017.05.023
- VernacularTitle:固醇调节元件结合蛋白在妇科肿瘤发病机制及靶向治疗中的研究进展
- Author:
Tao WANG
;
Jun LIU
- Keywords:
Sterol regulatory element-binding protein;
Gynecological tumors
- From:
Clinical Medicine of China
2017;33(5):471-474
- CountryChina
- Language:Chinese
-
Abstract:
Objective Sterol regulatory element-binding proteins(SREBPs) are a family of nuclear transcription factors that regulate lipid metabolism in eukaryotic cells.They are over expressedin many malignant tumors,and closely related to tumor initiation and progression.We briefly summarize the research advancement of SREBPs in gynecological tumors.