Distribution and antimicrobial resistance of methicillin-sensitive Staphy-lococcus aureus and methicillin-resistant Staphylococcus aureus in hospi-talized children
10.3969/j.issn.1671-9638.2017.07.002
- VernacularTitle:住院患儿MSSA与MRSA的分布特点及耐药性
- Author:
Yi LU
;
Liang DONG
;
Ji YANG
;
Xiuhong ZHANG
;
Xianlong GENG
- Keywords:
hospitalized children;
Staphylococcus aureus;
methicillin-resistant Staphylococcus aureus;
methicil-lin-sensitive Staphylococcus aureus;
drug resistance;
microbial
- From:
Chinese Journal of Infection Control
2017;16(7):596-599
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare distribution and antimicrobial resistance of methicillin-sensitive Staphylococcus aureus(MSSA)and methicillin-resistant Staphylococcusaureus(MRSA)in hospitalized children,and provide refer-ence for empirical use of antimicrobial agents.Methods Isolation and clinical data of Staphylococcus aureus (S. aureus)from hospitalized children in a hospital during 2011-2015 were analyzed retrospectively,distribution and antimicrobial resistance between MSSA and MRSA were compared.Results A total of 919 strains of S.aureus were isolated,632(68.77% )of which were MSSA,287(31.23%)were MRSA.65.03% of MSSA infection and 64.11% of MRSA infection were in children aged 29 day-1 year old.80.38% of MSSA and 79.09% of MRSA were isolated from sputum specimen.MSSA and MRSA were mainly distributed in department of pediatric respiratory medicine(50.73%,45.89% respectively)and department of pediatric neurology(22.98%,26.84% respectively). Resistance rates of MSSA to antimicrobial agents were<20.00% except penicillin and erythromycin;resistance rates of MRSA to penicillin,oxacillin,erythromycin,and clindamycin were all>40.00%;resistance rates of MR-SA to tetracycline,erythromycin,clindamycin,levofloxacin,ciprofloxacin,moxifloxacin,nitrofurantoin,and ri-fampin were all higher than MSSA.Conclusion MSSA is main S.aureus isolated from hospitalized children,in-fants under 1 year of age are the main population,the main distribution departments of MSSA and MRSA from re-spiratory tract specimen are similar,antimicrobial resistance of MRSA is generally higher than that of MSSA.
