Systematic evaluation on direct economic burden of healthcare-associated infection due to multidrug-resistant organisms

VernacularTitle:多重耐药菌医院感染直接经济负担的系统评价
Author: Ling LING ; Weixuan WU ; Shumei SUN ; Hao ZHOU ; Fang YU ; Qian XIANG
Keywords: healthcare-associated infection; multidrug-resistant organism; direct economic burden; systematic evaluation
From: Chinese Journal of Infection Control 2017;16(7):616-621
CountryChina
Language:Chinese
Abstract: Objective To understand the direct economic burden of healthcare-associated infection(HAI)due to multidrug-resistant organisms(MDROs).Methods Computer retrieval of CNKI,Wanfang,VIP,PubMed,Sci-enceDirect,and Cochrane databases on literatures about economic burden of MDRO HAI at home and abroad were performed,the retrieval time was from database establishment to December 2015,systematic evaluation of the liter-atures was obtained.Results According to the inclusion and exclusion criteria,as well as through Newcastle-Otta-wa Scale (NOS)for evaluating the literatures,19 literatures were included.In 12 studies about methicillin-resistant Staphylococcusaureus infection,the direct economic cost varied from $916.61 to $62908.00;in 4 studies about MDRO Acinetobacterbaumannii infection,the direct economic cost varied from$4644.00 to $98575.00.Direct economic cost due to extended-spectrumβ-lactamases-producing Enterobacteriaceae was $2824.14-$30093.00. Conclusion MDRO HAI will increase economic cost of both hospitals and patients,prevention and control measures should be taken .