Effect of ventilator circuit changes on incidence of ventilator-associated pneumonia:a systematic review
10.3969/j.issn.1671-9638.2017.07.007
- VernacularTitle:呼吸机管路更换时间对VAP发病率影响的系统评价
- Author:
Junxiang LIU
;
Hongqiong DING
;
Zhibi WANG
- Keywords:
ventilator-associated pneumonia;
pneumonia;
ventilator-associated;
ventilator circuit;
change inter-val;
systematic review;
Meta analysis
- From:
Chinese Journal of Infection Control
2017;16(7):622-626
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate systematically the effect of ventilator circuit changes on incidence of ventilator-associated pneumonia(VAP).Methods Literatures about the effect of ventilator circuit changes on occurrence of VAP were searched from PubMed,Cochrane Library,CNKI,VIP,and Wanfang database,incidence of VAP in pa-tients who received circuit changes at different intervals was compared,odds ratio (OR)and 95%CI were as effect index of the study,RevMan 5.2 software was used for data analysis.Results A total of 12 literatures were included,including 18003 patients using ventilators.According to the interval of ventilator circuit changes,patients were divided into 1-day group (n=191),2-day group(n=8932),3-day group(n=228),and 7-day group(n=8652).Meta analysis showed that circuit changed every 7 days had a lower risk of VAP than that changed once ev-ery day (OR,3.72[95%CI,1.50,9.23]),there was no significant difference in risk of VAP between 7-day group and 2-day group (OR,1.17[95%CI,1.00,1.37])as well as 7-day group and 3-day group(OR,0.77 [95%CI, 0.49,1 .23]).Conclusion Patients who received circuit changes every 7 days have a lower risk of developing VAP than those who received circuit changes once per day,so change the ventilator circuit in patients with mechanical ventilation every 7 days is more reasonable.
