EB virus infection with facial paralysis in children:a case report and literature review

VernacularTitle:儿童EB病毒感染伴面瘫1例报告并文献复习
Author: Qiguo ZHU ; Jingfang CHEN ; Xiaoxin LIN ; Jiancheng LIN ; Hui YU ; Qirong ZHU ; Jun SHEN
Keywords: EB virus; facial paralysis; acyclovir; treatment; child
From: Journal of Clinical Pediatrics 2017;35(7):516-518
CountryChina
Language:Chinese
Abstract: Objective To explore the treatment of children with EB virus infection accompanied by facial paralysis. Method The clinical data of a child with EB virus infection accompanied by facial paralysis was analyzed retrospectively, and the related literature were reviewed. Results A 2-year-old boy was admitted to hospital due to fever and mouth askew for 4 days. After admission, he was confirmed to have EB virus infection and viremia by serology and polymerase chain reaction, and then treated with acyclovir. The symptoms of facial paralysis and EB viremia disappeared completely 14 days after antiviral treatment. There was no recurrence in the short-term follow-up. Interestingly, the literature analysis shows that there is still limited evidence for the antiviral treatment by acyclovir in children with acute infection of EB virus associated with facial paralysis. Conclusion Antiviral treatment may be beneficial to EB viremia with facial paralysis.